Answer:
Basically the translation of CK-B protein is inhibited in the U937D cells, despite the fact that the CK-B protein is bounded to the ribosomes. This is because(<u>mechanisms)</u> the translation is inhibited by the binding of translational repressors to the 3’UTR of the CK-B mRNA rather than the actual CK-B mRNA 3'UTR.
Furthermore, the soluble protein inhibitions is due to the reaction of the U937 cells to the short RNA sequences with the 3’UTR.
<u>The introduction of these sequences(shot segement of RNA) </u>into the U937D cells leads to CK-B synthesis. This makes 3’UTR sequences to bind to the translational repressor proteins, thus preventing them from binding to the CK-B mRNA
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COMPLETED QUE.
A common feature of many eukaryotic mRNAS is the presence of a rather long 3' UTR, which often contains consensus sequences. Creatine kinase B (CK-B) is an enzyme important in cellular metabolism. Certain cells—termed U937D cells—have lots of CK-B mRNA, but no CK- B enzyme is present. In these cells the 5’ end of the CK-B mRNA is bound to ribosomes, the mRNA is apparently not translated. Something inhibits the translation of the CK-B mRNA in these cells. Researchers introduced numerous short segments of RNA containing only 3’UTR sequences into U937D cells. As result, the U937D cells began to synthesize the CK-B enzyme, but the total amount of CK-B mRNA did not increase. The introduction of short segments of other RNA sequences did not stimulate the synthesis of CK-B; only the 3’UTR sequences turned on the translation of the enzyme. Based on these results, <u>purpose a mechanism for how CK-B translation is inhibited in U937D cells. Explain how the introduction of short segments of RNA containing the 3'UTR sequences might remove the inhibition.</u>
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Explanation:
Answer:
Habitat destruction and degradation, illegal shooting, and the contamination of its food source, largely as a consequence of DDT, decimated the eagle population.
<span>The F2 generation would have included a higher percentage of pea plants producing round, yellow peas. As the f2 generation included 315 plants producing round yellow peas, 108 with round green peas, 101 with wrinkled yellow peas, and 32 with wrinkled green peas which all are in the ratio 9:3:3:1.</span>
Answer:
A phenotype is the physical observations of anything, really. For example, lazuli bunting (a bird species) has feathers that range from dull brown to bright blue. the dull brown and bright blue birds are best at mating. adult males are aggressive toward the bluish-brown birds. The greatest frequency here is that 2 seperate colors are able to mate best, yet, the mixed birds are attacked.
Explanation:
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