-Demographic factors such as age, ethnicity, gender, education, marriage status
-Psychosocial factors: beliefs, motivation, attitude
-Patient-prescriber relationship
-Health literacy
-Patient knowledge
-Physical difficulties
-Tobacco or alcohol intake
-Forgetfulness
-History of compliance
-Treatment complexity
-Duration of treatment
-Medication side effects or taste
-Degree of behavioral change required
-Requirements for drug storage
-Lack of accessibility
-Long waiting time
-Difficulty getting prescriptions
-Unhappy clinic visits
-Inability to take time off work
-Cost and income
-Social support
-Disease symptoms
-Severity of the disease
