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julsineya [31]
2 years ago
11

What amino acid can be obtained by the reductive amination of γ-ketoglutaric acid

Biology
1 answer:
Svetradugi [14.3K]2 years ago
5 0

Answer:

Glutamic acid

Explanation:

Reductive amination is a form of amination that involves the conversion of a carbonyl group to an amine via an intermediate imine. The carbonyl group is most commonly a ketone or an aldehyde. In this reaction, in the presence of enzyme glutamate dehydrogenase, ammonium ion directly combines with alpha-ketoglutaric acid, to form glutamic acid (amino acid) and for this to happen, a reduced coenzyme (NADPH) is required.

The biosynthesis of glutamic acid  can be obtianed from the reductive amination of γ-ketoglutaric acid

γ-Ketoglutaric acid is a common precursor in synthesis of glutamic acid. Addition of NADPH and ammonia or alpha amino acid with   γ-Ketoglutaric acid produces glutamic acid. Enzymes involved in this reduction amination  process are glutamate dehydrogenase and/or transaminase.

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Answer:

  • The statements that apply are the third and the fourth.

Explanation:

Since the <em>mice crossed</em> were <em>pure breeding</em>, each parent<em> produced sperms of one kind</em>, both alleles of each parente were equal. Thus, the first (A) and second (B) statements are false.

Assume <em>pure breeding black mice</em> produced BB sperm and <em>pure breeding brown mice</em> produced bb sperm.

The punnett square for the first generation, F₁ is would be:

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This is, all the <em>F₁ generation</em> mice are Bb.

All the <em>992 in F₁ generation had black coats</em> means <em>black is dominant</em>.

Now when F₁ generation is crossed, the punnet square reveals the second generation, F₂:

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B        BB    Bb

b         bB    bb

The brown allele that was hidden now appears.

Based on the assumption that black is dominant, BB, Bb and bB are black, which is 3/4 or 75%. This, is 75% of the mice in the F₂ genrertion are black.

The combination bb is brown. Thus, 1/4 or 25% of the mice in the F₂ generation are brown.

When the mice in the first generation were crossed, they yielded 961 black coated mice and 317 brown coated mice. That is:

  • Total mice: 961 + 317 = 1278
  • Proportion of black mice: 961 / 1278 ≈ 0.75 = 3/4
  • Proportion of brown mice: 317 / 1278 ≈ 0.25 = 1/4
  • Ratio black to brown: 3 to 1.

Therefore, it is proven that an approximately three-to-one ratio of black to brown cated mice in F₂ is accounted fro the black allele being dominant over the  brown allele (choice C.)

Also, the brown allele is not independent from the black allele and dissapears in the F₁ generation: it is not independent because it presence will only be shown when the black allele is not present, and it is said that it dissapears because it is not revealed, it is hidden.

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