Answer:
The correct answer is "all of the above".
Explanation:
The missing options of this question are:
A. The major etiologic factor associated with SC is ultraviolet radiation, principally UV-B.
B. Factors predisposing to SC include skin phenotype, age, male sex, outdoor occupation, rural living, and host immune status.
C. AK and SC serve as clinical dose-meters for chronic UVR exposure.
D. All of the above.
The correct answer is option D. "All of the above".
Solar cheilosis (SC) is a type of precancer of the lower lip, induced by ultraviolet light exposure, particularly by the exposure of UV-B from sunlight. However, UV-B exposure is not the only cause of SC, there are different factor that predispose to the development of this disease, including skin phenotype, age, male sex, outdoor occupation, rural living, and host immune status. Particularly because people with an outdoor occupation is more expose to sunlight and people with an detrimental immunological condition cannot fight SC as easy as a healthy person. According to the scientific article "Epidemiology of actinic keratoses and squamous cell carcinoma" by Salasche SJ., Actinic keratosis (AK) and SC serve as clinical dose-meters for chronic UVR exposure
