Answer:
The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.
In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.
Explanation:
Hi,
Answer: The Liver
<u>My work:</u> Carbohydrates are usually located and converted in the Liver.
<u><em>Extra Information:</em></u> The body uses Carbohydrates as glucose. From there glucose can be converted to glycogen.
<u><em>Words you might not know:</em></u>
1) Converted - To change.
2) Glucose - Energy source.
3) Glycogen - Stores Carbohydrates
I Hope I Helped!
<em>~KingJupiter</em>
Answer: c. 0.15%
Explanation:
The blood alcohol concentration or BAC refers to the percentage of alcohol present in the bloodstream. The value of blood alcohol concentration of 0.15% is very high. It will affect the balance of voluntary muscles, walking and talking will also become difficult. The person will experience a severe increase in the rate of heart, the body temperature will rise, the person will experience irregular breathing and the bladder control will become weak.
Answer:Option B
The memory response is due to long lived cells that can respond rapidly to second exposure.
Explanation:
Immunological memory is the ability of the immune system to quickly identify and remember an antigen from a pathogen that the body has encountered before and initiate a faster immunological response upon a reencounter with the particular antigen. This dependents on colonial selection.. The memory cells have a long life span and can remain in the body for a long time. When it encounter the antigen its previously encountered for the second time, they mobilize quickly and become plasma cells, these secrets a lot of antibodies and cause a stronger reaction to defend against such antigen in a short time.