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VLD [36.1K]
2 years ago
4

Why does the effect of the cholera toxin on the epithelial sodium transport protein contribute to both the diarrhea and metaboli

c acidosis?
Biology
2 answers:
givi [52]2 years ago
8 0

The cholera toxin binds to GM1 ganglioside receptors on the enterocytes (epithelial cells of intestines). This results in the uptake of the toxin by endocytosis. Once inside the cells, the toxin undergoes a biological pathway that causes an increase in the production of cyclic-AMP. This activates the cystic fibrosis transmembrane conductance regulator (CFTR) thereby resulting in an efflux of ions (mostly sodium) from the cells. Water efflux follows due to a change in osmotic pressure thereby causing watery diarrhea.






Airida [17]2 years ago
5 0

Answer:

The cholera toxin in the sodium epithelial transport protein promotes the release of cyclic adenosine monophosphate in the cells of the intestinal mucosa, promoting diarrhea and metabolic acidosis.

Explanation:

Cholera toxin has the ability to bind sodium transport protein. as a result, the protein will bind to the intestinal mucosa and promote the exaggerated release of cyclic adenosine monophosphate into the cells of the intestinal mucosa. This molecule stimulates the release of water and salt, which will promote diarrhea and metabolic acidosis.

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Of the three major groups of forensic science professionals, which of the following provide specific knowledge in an area of sci
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Answer:

A. associate scientists

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2 years ago
New oceanic lithosphere is unable to form at mid-ocean ridges. Please select the best answer from the choices provided T F
miss Akunina [59]
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A gel electrophoresis migration pattern displaying polymerase chain reaction (PCR) products shows four strong bands. The lengths
dangina [55]

Answer:

D) The encoded protein contains four repeats of a specific sequence.

Explanation:

The polymerase chain reaction is a technique used to replicate or amplify the amount of DNA sample.

The technique employs running the DNA samples on the gel through which the DNA samples run based on their sizes.

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In the given question, four sizes of DNA bands are formed in the ratio of  1:2:3:4 which shows that the proteins encoded by this DNA have four repeats of a specific sequence of the template strand. This was confirmed when the largest band sample was again used as a sample of PCR and the PCR resulted in the four bands in similar  1:2:3:4.  

Thus, Option-D is the correct answer.

3 0
2 years ago
4a) From the sequence below, identify which portion could be a transmembrane helix. Please underline the portion you select in y
arlik [135]

Answer:

FRYVNGPVLIRKLYSWWNLIMILLQYFAIMGNLVMNLVMNTGDVNELTANTITT

The bold region of the above sequence will be in the transmembrane region.

4.b) To predict the helix we need to know the propensity of each amino acid in the amino acid sequence to form an alpha helix of the protein. Not only the propensity of a single amino acid will dictate that but also other amino acids in its vicinity will have an effect on it. More importantly, that should follow the Ramachandran plot.

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7 0
2 years ago
A worker standing on a freshly mopped floor is adjusting products on a metal shelf. There is an exposed wire in contact with the
Semenov [28]

Answer: Workplace electrocusion

Explanation:

The human body is a good conductor of electricity. The workplace electrocution occurs due to electric shock. This leads to workplace injuries that may often lead to disabilities and can also be fetal. The workplace electrocution can also lead to cardiac arrest, and tissue damage due to thermal burns. The severity of injuries may depend upon the intensity of electricity, health of the victim and how the current flows in the body.

According to the given situation, the freshly mopped floor is a source of water and water, as well as metal, which is a good source of electricity. The electric wire is an energized source of electrical energy that will allow the flow of electric current in the body, as well as contact with the floor containing water, which will enhance the effect. Thus this is an example of workplace electrocution.

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2 years ago
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