Replication may be defined as the process of formation of the daughter DNA from the parent DNA with the help of enzymes and proteins. The three main process of replication are inititation , elongation and termination.
The double stranded DNA molecule undergoes the process of replication. Four different dNTPs - adenine, guanine, thymine and cytosine are required for the process of replication. Primers are required for initiation of the process of replication and ori region is the inititaion point of replication.
To denature a protein is to alter its three dimensional structure. Loss of protein structure consistently correlates with loss of protein function, so it is a strong correlation.