Question

Which of the following best describes the mechanism by which steroid hormones control gene expression? View Available Hint(s) Which of the following best describes the mechanism by which steroid hormones control gene expression? Steroid hormones transport mRNA from the nucleus into the cytoplasm, where it is translated into protein. Chaperone proteins transport steroid hormones into the cell and guide them to their target genes. Steroid hormones that enter the cell activate receptors. These hormone-receptor complexes then bind HREs and influence gene expression. Steroid hormones enter a cell, bind directly to hormone response elements (HREs), and enhance transcription.

Answer 1

Answer:

Steroid hormones that enter the cell activate receptors. These hormone-receptor complexes then bind HREs and influence gene expression.

Explanation:

Mechanism of action of steroid hormones is as follows:

• Steroid hormone enters cell and bind to the receptor.
• Translocation of activated receptor- ligand complex into nucleus.
• This complex then bind to another receptor on the chromatin.
• Steroid receptors form dimers.
• Act on DNA

• These hormone-receptor complexes then bind HREs and influence gene expression.
• Augmentation or Suppression of transcription.

Answer 2

Answer:

The correct answer is "Steroid hormones that enter the cell activate receptors. These hormone-receptor complexes then bind HREs and influence gene expression".

Explanation:

Steroid hormones control gene expression by the interaction with tissue-specific binding sites. The steroid hormones  that enter the cell activate receptors, which are highly specific and have a high affinity with them.  These hormone-receptor complexes then bind to hormone response elements (HREs), which are short sequence of DNA that influence gene expression by producing effects such as chromatin remodelling.