Question

Destruction of which pancreatic cells would cause hyperglycemia? alpha cells beta cells delta cells none of the choices are correct.

Answer 1

Destruction of the pancreatic "Beta Cells" can lead to hyperglycemia is enough of them are annihilated. This is because the beta cells of the organ the pancreas are responsible for producing the hormone insulin, whose job is to lower blood-glucose levels when they rise (as after a high-carbohydrate meal).
Without enough insulin secreted by beta cells, glucose levels will continue to rise in the blood plasma, a condition called hyperglycemia.
This is actually the main cause of insulin-dependent diabetes mellitus (IDDM, aka Type 1 Diabetes).