Humans are more closely related to hogs than hogs are to guinea pigs.
Explanation:
The difference in the amino acid sequence of a protein is used to know the relation between organism i.e. how closely they are related.
It is known that proteins are the result of DNA sequence ie genes of the organism.
The gene or protein is compared between organisms to understand the evolutionary evidence and similarities between them.
The less is the difference the more is the two organisms closely related as in the case of hog and human which have only 1 amino acid difference in their insulin enzyme. While guinea pig is having a difference of 17 amino acids so it is expected to be distantly related.
These relations helps the scientist to resolve the issues of crisis say insulin. They zero out the possibility of extracting the enzyme genes of possible organism and increase the yield.
Answer:
Play Therapy
Explanation:
Play therapy is a type of psychotherapeutic orientation by which play is used as a medium to help an individual, most especially children, to express their feelings. This therapy helps with the brain development of a child and enables a play therapist respond to the needs of a child, most especially the metal health needs.
Through play therapy, a child is naturally able to communicate his feelings as he is guided, and this helps children to become aware of themselves ad accept who they are.
<h2>GPCRs,RTKs</h2>
Explanation:
G Protein Coupled Receptors(GPCRs) are more common and found in almost all eukaryotes whereas Receptor Tyrosine Kinases(RTKs) are second largest family of receptors that relay signal from cell surface to the interior
- G protein coupled receptors(GPCRs) interacts with the ligand activated GPCR and phosphorylates its intracellular domain.This process of phosphorylation can terminate signal or desensitize receptor
- Autophosphorylation of receptor can initiate signal in case of Receptor Tyrosine Kinases(RTKs);Autophosphorylation is a feature of RTKs in which receptor dimerization activates intrinsic tyrosine kinase activity by which they phosphorylate its own tyrosine residue on cytosolic phase
- Seven transmembrane helices can be seen in case of G protein-coupled receptors(GPCRs);transmembrane protein of it consists of single polypeptide and spans the membrane 7 times
- Insulin receptor is a part of Insulin Signalling which comes under RTKs;Insulin receptor always exist in case of dimeric form
- Epinephrine receptor is an example of GPCRs;Epinephrine is an endocrine hormones produced in stress condition
- Transmembrane protein of GPCR activates G protein,activated G protein binds with effector enzyme and activate it;effector enzyme further can produce or destroy secondary messenger