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Volgvan
2 years ago
3

Considering the relative binding affinities and adenylate cyclase activity as a function of hormone concentration, what can you

conclude about the mechanism of action of the hormone–receptor complexes?
Biology
1 answer:
ollegr [7]2 years ago
3 0

Answer:

The binding affinity almost perfectly matches the ability to stimulate adenylate cyclase, suggesting that the hormone-receptor complex leads to the stimulation of adenylate cyclase.

Explanation:

Bound receptor interacts with and, through a set of G proteins, turns on adenylate cyclase, which is also an integral membrane protein. Activated adenylate cyclase begins to convert ATP to cyclic AMP, resulting in an elevated intracellular concentration of cAMP.

Adenylyl cyclase (ADCY, EC number 4.6. 1.1), also known as adenylate cyclase, is an enzyme which catalyzes the cyclization of adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP) which requires the cleavage of pyrophosphate (PPi).

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Using the sliding flament theory, explain (or draw) the process of sarcomere shortening. Start from the point where calcium woul
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Answer:

  1. Calcium binds to troponin C
  2. Troponin T moves tropomyosin and unblocks the binding sites
  3. Myosin heads join to the actin forming cross-bridges
  4. ATP turns into ADP and inorganic phosphate and releases energy
  5. The energy is used to impulse myofilaments slide producing a power stroke
  6. ADP is released and a new ATP joins the myosin heads and breaks the bindings to the actin filament
  7. ATP splits into ADP and phosphate, and the energy produced is accumulated in the myosin heads, starting a new cycle
  8. Z-bands are pulled toward each other, shortening the sarcomere and the I-band, producing muscle fiber contraction.

Explanation:  

In rest, the tropomyosin inhibits the attraction strengths between myosin and actin filaments. Contraction initiates when an action potential depolarizes the inner portion of the muscle fiber. Calcium channels activate in the T tubules membrane, releasing <u>calcium into the sarcolemma.</u> At this point, tropomyosin is obstructing binding sites for myosin on the thin filament. When calcium binds to troponin C, troponin T alters the tropomyosin position by moving it and unblocking the binding sites. Myosin heads join to the uncovered actin-binding points forming cross-bridges, and while doing so, ATP turns into ADP and inorganic phosphate, which is released. Myofilaments slide impulsed by chemical energy collected in myosin heads, producing a power stroke. The power stroke initiates when the myosin cross-bridge binds to actin. As they slide, ADP molecules are released. A new ATP links to myosin heads and breaks the bindings to the actin filament.  Then ATP splits into ADP and phosphate, and the energy produced is accumulated in the myosin heads, which starts a new binding cycle to actin. Finally, Z-bands are pulled toward each other, shortening the sarcomere and the I-band, producing muscle fiber contraction.

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One factor that could account for a drop in the water table is
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Rem sleep is also called _____ because the brain is aroused and active while the person remains nonresponsive and asleep.
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Sally is a 41 year old female with a history of unsuccessful weight loss attempts. In the past, Sally has tried "almost every di
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Answer:

the approach has been described below

Explanation:

I will have to use motivation as a way of enhancing change in the life of Sally. From this question, she seems to be a lonely lady, with low self-esteem and no physical activity. The first thing I would do is to help to get her out of monotony by motivating her.

Once motivated, I would help plan her diet and add combinations of physical activities. These activities may include walking and running. With time an expert would take over her physical training.

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