Question

Part A In receptor-mediated endocytosis, receptor molecules initially project to the outside of the cell. Where do they end up after endocytosis? In receptor-mediated endocytosis, receptor molecules initially project to the outside of the cell. Where do they end up after endocytosis? on the inside surface of the cell membrane on the outer surface of the nucleus on the inside surface of the vesicle on the outside of vesicles

Answer 1

The correct answer is: on the inner surface of the vesicle.

Explanation:

• Receptor-mediated endocytosis can be defined as the process by which molecules present outside the cell in the external environment are transferred to the interior of the the cell by the help of certain receptor molecules located on the cell surface.
• These receptor molecules are highly specific for the particular molecules those they internalize into the cell.
• The target molecules specifically bind to their cognate receptors present on the surface of the cell.
• This signals the plasma membrane to undergo an invagination towards the interior of the cell thereby forming an incomplete vesicle-like structure.
• This structure is formed such that the outer part of the plasma membrane faces the interior surface of the vesicle-like structure, hence, the target molecule bound receptor which was initially facing the cell exterior now faces the interior surface of the vesicle-like structure.
• Finally, this structure pinches or buds off from the plasma membrane to the cell interior resulting in the formation of the complete vesicle with the target molecule bound receptor facing the interior surface of the vesicle.