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Aloiza [94]
2 years ago
13

(d) Researchers discovered a strain of C. parvum that expresses a functional variation of the lactate dehydrogenase gene. A DNA

sequence comparison showed that the variant differs from the normal sequence in the region that codes for the enzyme’s allosteric site. Predict the effect of FX11 treatment on C. parvum cells that express this variant of lactase dehydrogenase. Provide reasoning to support your prediction. Explain how gossypol and FX11 might be used as drugs to treat C. parvum infections in humans without negatively affecting human cells.
Biology
1 answer:
Gelneren [198K]2 years ago
3 0

Answer:

Changing the allosteric site would definitely impact the sensitivity of the blocker, and we can not understand precisely how it is owing to our lack of awareness of the specific adjustments and the FX11 layout.

Explanation:

The move would most likely reduce affinity, and FX11 will no longer be as successful as inhibiting C. Growth of parvum. An inhibitor may reach an allosteric site since the site has some sizes and operational classes that precisely match the shape and operational categories of the inhibitor, which is how the association is obtained if the shape is modified and the inclination is affected.

Such chemicals can be used as human drugs because the mechanism we 're disrupting isn't that normal in human cells, we 're talking about lactic fermentation. C.parvum is a parasite that is present in the digestive tract, and these areas do not appear to experience aerobic glycolysis. The material that undergoes this process under other conditions is muscle tissue. It is possible that the absorbed drug can penetrate the bloodstream and touch other organs, and we would recommend that clinicians avoid exercise during this drug therapy.

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Answer:

1. Using the map and the minimal knowledge that Liz has at this point, propose three different hypotheses regarding the sudden high mortality of marine iguanas. Record your answers in the worksheet and post your hypotheses to the 03.01 class discussion board before proceeding to the next question.  (3 points possible)

Hypotheses One:  Iguanas are adapted to hot/warm weather, so the weather changed could have affected them.

Hypotheses Two: There was not enough shelter for the iguanas so they started disappearing.

Hypotheses Three: A new species has come close to where the iguanas live and taken them out.

2. Look at your classmates’ hypotheses on the discussion board. Choose one hypothesis that seems most likely to you. Provide the student name and hypothesis and tell what evidence you would need to support (or refute) it. (3 points possible)   Carter Spiers, Hypothesis 1. there was a lot of rain and it washed at the iguanas away. We would have to dive into the water/ ocean and find iguana bodies to be able to prove that this is true.

3. Given what you know at this point about marine iguanas and the abiotic effects of ENSO, develop two possible directions of research that Liz should pursue to understand exactly why the iguanas suffered such a high mortality. Keep in mind that you need to consider indirect effects. While environmental temperature does change metabolic rates of ectotherms, the iguanas are exposed to a wide range of temperatures as they feed and bask on the lava. Direct mortality in response to a temperature change of a couple of degrees is unlikely.  (3 points possible)

Possible Research Direction One: The climate event caused a lot more rainfall which then made it very hard for the iguanas to reach their food source.

Possible Research Direction Two: The temperatures raised very high causing the iguanas to absorb a extreme about of extra heat, which eventually made them very lazy and stopped defending their self from predators.  

4. Choose one of those directions of research and determine what data you would need to find to support your ideas.  (2 points possible)          Specific data of the extreme amounts of rainfall.

Explanation:

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2 years ago
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Melatonin

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  • The pineal gland is turned on when there is darkness and turned off when there is light.
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Answer:

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2. emits toxins through combustion – Incinerators produce dioxins which is a dangerous chemical

3. drains liquids into the ground – Land fill, leachate is a common issue with all landfill site.  

4. releases greenhouse gases – Both, methane and other carbon gases are produced in both landfill and incinerators

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6. generate ash – Incenerator only

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