Answer:
True
Explanation:
When the resting potential of the membrane is changed, the membrane becomes either more negative inside or less negative. This small deviation from the resting potential is called graded potential. A graded potential occurs when a stimulus triggers opening or closing of the mechanically gated or ligand-gated channels present in the plasma membrane.
For example, the presynaptic neuron releases neurotransmitters in response to a nerve impulse. The neurotransmitter binds to receptors present in the plasma membrane of the postsynaptic neuron and triggers the opening of the ion channels to allow the inflow of particular ions to flow. The flow of ions changes the voltage across the membrane. This change in membrane voltage is a postsynaptic potential and is a type of graded potential.
Answer:
If predominantly, we can't say of any treatment for progeria, aside from the routine observation of heart and blood vessel (cardiovascular) disease which is important in taking care of the health situation in the affected kids. Treatment relies majorly on the situation and clinical manifestations of the kid. At first, in 1999, the findings of the initial clinical drug trial for kids with an unusual rapid-aging disease, often referred to as Progeria, revealed positive results with a farnesyltransferase inhibitor (FTI), a drug initially designed to treat cancer.
The PATHWAY in gene expression to be TARGETED is progenin formulation---
The Progeria-forming mutation results in the formation of the protein progerin that disrupts the cell activities. Some areas of progerin's toxic impact on the body is due to the formation of a farnesyl group, Â that adheres to the progerin protein aiding it's disruption of the body's cells. FTIs means of action is through inhibition of the adhesion of the farnesyl group to progerin, decreasing the hazardous substances that leads to progerin.
The genetic medicine technique that acts as.an intervention tool gene therapy to regulate the gene that causes the stimulation and formation of the protein progenin.
Escalated cardiovascular disease results in death in the case of Progeria.
It's worthwhile to note that if the basic blood vessels can with time get better as a result of treatment, the treatment shows positive results. Slowing down stroke and aging manifestations will boost the chances of treatment.
They would die or have to have food digested for them.
It is a White Blood Cell hope this helps! ^0^
