Question

Cells of the pancreas will incorporate radioactively labeled amino acids in to proteins. This "tagging" of newly synthesized proteins enables a researcher to track their location. In this case, we are tracking an enzyme secreted by pancreatic cells. What is its most likely pathway

Answer 1

Answer:

The most likely pathway is ER - Golgi - vesicles that fuse with plasma membrane.

Explanation:

The endomembrane system is an extensive sets of intracellular membrane. These system was first discovered in the late 1800s when scientist Camillo Golgi noticed that a certain stain selectively marked only some internal cellular membranes. Golgi actually thought that these intracellular membranes were interconnected, but advances in microscopy and biochemical studies of the various membrane-encased organelles later made it clear the organelles in the endomembrane system are separate compartments with specific functions.

Answer 2

Answer: the question is incomplete,below is the complete question.

Cells of the pancreas with incoperate radioactively labelled amino acids into proteins. this "tagging" of newly synthesized proteins enables a researcher to track the location of these proteins in a cell. In this case we are tracking an enzyme that is eventually secreted by pancreatic cell. Which of the following is the most likely pathways for movement of these proteins in the cell?

A. ER - Golgi to nucleus

B. Golgi - ER - lysosomes

C Nucleus - ER- Golgi

D. ER - Golgi - vessicles that fuse with plasma membrane

E. ER - lysosomes - vessicles that fuse with plasma membrane

Explanation: The correct answer is option D

ER - Golgi - vessicles that fuse with plasma membrane

The acinar cell of the endocrine pancreas (secretes into the blood stream) has a highly developed endoplasmic reticulum (ER) system combined with mechanisms to modify and transport newly synthesized proteins through the secretory pathway. In addition to its functions in performing protein synthesis and processing.

Each protein synthesized in the ER must undergo specific secondary modifications as well as folding in order for it to be properly transported to destination organelles, such as Golgi, zymogen granule (storage for the digestive enzymes) and lysosome or membrane sites (vessicles that fuse with plasma membranes).

protein processing in the ER could be adversely affected by environmental factors, such as alcohol, smoking, altered metabolism and xenobiotics.