Answer:
A 22 to 25 amino acid sequence present in the central section of the protein, which gives rise to an alpha helix in the membrane is known as the stop-transfer anchor sequence. The sequence plays an essential function in targeting the protein towards the plasma membrane. On the other hand, it also ceases targeting of the protein towards the endoplasmic reticulum, which was started by the signal peptide.
Thus, the process of translation of the remaining of the protein occurs within the cytosol due to the tethering of the transmembrane domain. In the stop-transfer anchor sequence, the hydrophobic amino acids present are isoleucine and valine. After mutation, these amino acids get converted into arginine and lysine, thus, hydrophilic amino acids replace hydrophobic amino acids in the sequence.
Due to this, the transmembrane domain cannot be targeted towards an integral part of the plasma membrane by the short transfer anchor sequence, and therefore, now the translocation of the protein will take place towards the endoplasmic reticulum as initiated by the signal peptide at the beginning.
In deprived of triose phosphate isomerase, only one of the two three-carbon molecules produced by aldolase might be used to produce ATP in which only two molecules of ATP would outcome from the metabolism of each molecule to glucose but two molecules of ATP would still be essential to form fructose 1,6-biphosphate, the sub state for aldolase. The net yield of ATP would be 0, a yield incompatible with life.
Answer: Option C.
Both
Explanation:
Streptomycin is an antibiotics produced from bacteria and fungi and it is used to treat bacteria infections (prokaryotic ) such as tuberculosis, mycobacterium infection e.t.c.
It's inhibit protein function in prokaryotes because it's affects the function and performance of 70 s RIBOSOMES which is an organelles for protein production.
Streptomycin does not affect eukaryotes because it does not bind to the RIBOSOMES of eukaryotic cells which in turn does not affect protein production.
In patient-centered care, all healthcare decisions and quality measurements are driven by the individual's specific health needs and desired health outcomes. The patient is always a partner to the health care provider, thus following these eight principles. (1)respects for patient's values, preference and expressed needs; (2)coordination and integration of care; (3) information and education; (4)physical comfort; (5) emotional support and alleviation of fear and anxiety; (6) involvement of family and friends; (7)continuity and transition; and (8)access to care. Mrs Zahari is considered to receive effective, safe and patient-centered care if she is treated not only on the clinical perspective but also on the emotional, mental, social, spiritual and financial perspective and the health care provider follows the eight principles of patient-centered care.
