Answer:
If predominantly, we can't say of any treatment for progeria, aside from the routine observation of heart and blood vessel (cardiovascular) disease which is important in taking care of the health situation in the affected kids. Treatment relies majorly on the situation and clinical manifestations of the kid. At first, in 1999, the findings of the initial clinical drug trial for kids with an unusual rapid-aging disease, often referred to as Progeria, revealed positive results with a farnesyltransferase inhibitor (FTI), a drug initially designed to treat cancer.
The PATHWAY in gene expression to be TARGETED is progenin formulation---
The Progeria-forming mutation results in the formation of the protein progerin that disrupts the cell activities. Some areas of progerin's toxic impact on the body is due to the formation of a farnesyl group, Â that adheres to the progerin protein aiding it's disruption of the body's cells. FTIs means of action is through inhibition of the adhesion of the farnesyl group to progerin, decreasing the hazardous substances that leads to progerin.
The genetic medicine technique that acts as.an intervention tool gene therapy to regulate the gene that causes the stimulation and formation of the protein progenin.
Escalated cardiovascular disease results in death in the case of Progeria.
It's worthwhile to note that if the basic blood vessels can with time get better as a result of treatment, the treatment shows positive results. Slowing down stroke and aging manifestations will boost the chances of treatment.
Answer:
The correct statements are a, b and d. The incorrect statements are c and e.
Explanation:
Substrate level phosphorylation signifies the generation of ATP from ADP and a phosphorylated intermediate. On the other hand, in oxidative phosphorylation, the formation of ATP takes place from ADP and Pi, that is, an inorganic phosphate.
In substrate-level phosphorylation an enzyme is needed for the reaction to take place. In the process, a dissociation of bond takes place between an organic molecule and a phosphate prior to the formation of ATP. In this, one of the substrates is a molecule obtained from the dissociation of glucose.
In substrate-level phosphorylation, the enzyme taking part in the synthesis of ATP is not required to get attached to the membrane to generate ATP. The phosphate group, which is added to ADP to produce ATP does not come from free inorganic phosphate ions.
Answer:
Option A and C and D
Explanation:
Gylcogen is synthesized through a series of reactions through the assistance of enzymes. When glucose enter into the cell, it is converted into glucose 6-phosphate and then into glucose 1-phosphate and finally into uridine 5ʹ-diphosphate-glucose. In glycogenesis, glycogen is broken down into glucose 1-phosphate with the help of two glycogen phosphorylase. In the next stage the glycogen debranching enzyme untangles the branch points.
Hence, option A and C and D are correct
FIBRE B
is the answer
becausee
it is
