Barbiturates, including "truth serums" seen in movies like Meet the Fockers and sedatives that may have led to the untimely deat
h of Jimi Hendrix, are often synthesized using what type of reaction sequence involving two consecutive enolate alkylations
1 answer:
Answer:
Explanation:
Diethyl malonate is more acidic than monocarbonyl compounds (pKa=13) due to their alpha hydrogens being attached to two carbonyl groups. Thus, the <u>malonic ester is easily converted to its enolate ion by reaction with sodium ethoxide in ethanol</u>. The product of the alkylation of the malonic ester leaves a <u>hydrogen atom acid in an alpha position</u>, so the alkylation process can be repeated a second time to produce a dialkylated malonic ester.
In this case, when urea is treated with diethyl malonate in the presence of sodium ethoxide base,<u> the second alkylation step occurs intramolecularly</u> to generate a cyclic product, barbituric acid.
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<u>Answer:</u> The mass of sodium acetate that must be added is 30.23 grams
<u>Explanation:</u>
To calculate the number of moles for given molarity, we use the equation:
Molarity of acetic acid solution = 0.200 M
Volume of solution = 1 L
Putting values in above equation, we get:
To calculate the pH of acidic buffer, we use the equation given by Henderson Hasselbalch:
We are given:
= negative logarithm of acid dissociation constant of acetic acid = 4.74
pH = 5.00
Putting values in above equation, we get:
To calculate the mass of sodium acetate for given number of moles, we use the equation:
Molar mass of sodium acetate = 83.06 g/mol
Moles of sodium acetate = 0.364 moles
Putting values in above equation, we get:
Hence, the mass of sodium acetate that must be added is 30.23 grams
Answer : The final temperature of the copper is,
Solution :
Formula used :
where,
Q = heat gained = 299 cal
m = mass of copper = 52 g
c = specific heat of copper =
= final temperature = ?
= initial temperature =
Now put all the given values in the above formula, we get the final temperature of copper.
Therefore, the final temperature of the copper is,