In your discussion consider a SN2 reaction mechanism concept. Propose a modification of experimental procedure that would improv
e reaction yield. Give an example of another method of ether synthesis. Illustrate it with drawn reaction scheme; describe it in few sentences.
1 answer:
Answer:
Here's what I get
Explanation:
You may have done a Williamson synthesis of guaifenesin by reacting guaiacol with 3-chloropropane-1,2-diol.
A. Mechanism
Step 1
NaOH converts guaiacol into a phenoxide ion.
Step 2
The phenoxide acts as the nucleophile in an SN2 reaction to displace the Cl from the alkyl halide.
B. Improve the yield
You probably carried out the reaction in ethanol solution — a polar protic solvent.
You might try doing the reaction in a polar aprotic solvent— perhaps DMSO.
A polar aprotic solvent does not hydrogen bond to nucleophiles, so they become stronger.
C. Another method of ether synthesis —dehydration of alcohols
Sulfuric acid catalyzes the conversion of primary alcohols to ethers.
This is also a nucleophilic displacement reaction.
Protonation of the OH converts it into a better leaving group.
Attack by a second molecule of alcohol forms the protonated ether.
A molecule of water then removes the proton.
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Reactions of Ethyl-3-pentenoate with all given reagents are given below.
Reaction with H₂ / Pd:
The non-polar double bond present in Ethyl-3-pentenoate is reduced to saturated chain. This reagent can not reduce the carbonyl group.
Reaction with NaBH₄:
Sodium Borohydride is a weak reducing agent at compared to LiAlH₄. It can only reduce aldehydes and Ketones to corresponding alcohols.
Reaction with LiAlH₄:
Lithium Aluminium hydride is a strong reducing agent. It can reduce all types of carbonyl compounds to corresponding alcohols, But, it can not reduce non-polar double bonds like alkenes and alkynes.
Result:
The correct answer is Option-A (Highlighted RED below).
Reaction with H₂ / Pd:
The non-polar double bond present in Ethyl-3-pentenoate is reduced to saturated chain. This reagent can not reduce the carbonyl group.
Reaction with NaBH₄:
Sodium Borohydride is a weak reducing agent at compared to LiAlH₄. It can only reduce aldehydes and Ketones to corresponding alcohols.
Reaction with LiAlH₄:
Lithium Aluminium hydride is a strong reducing agent. It can reduce all types of carbonyl compounds to corresponding alcohols, But, it can not reduce non-polar double bonds like alkenes and alkynes.
Result:
The correct answer is Option-A (Highlighted RED below).
Mass of lead (II) chromate is 51 g. The molecular formula is and its molar mass is 323.2 g/mol
Number of moles can be calculated using the following formula:
Here, m is mass and M is molar mass.
Putting the values,
Therefore, number of moles of lead (II) chromate will be 0.1578 mol.
84.34 grams of grams of iron (III) chloride that can be produced is maximum because Fe is the limiting reagent in this reaction and chlorine gas is excess reagent.
Explanation:
Balanced chemical equation:
2 Fe + 3 Cl2 → 2 FeCl3
DATA GIVEN:
iron = atoms
mass of chlorine gas = 67.2 liters
mass of FeCl3 = ?
number of moles of iron will be calculated as
number of moles =
number of moles =
number of moles = 0.52 moles of iron
moles of chlorine gas
number of moles =
Putting the values in the equation:
n = (atomic mass of chlorine gas = 70.96 grams/mole)
= 947.01 moles
Fe is the limiting reagent so
2 moles of Fe gives 2 moles of FeCl3
0.52 moles of Fe will give
=
0.52 moles of FeCl3 is formed.
to convert it into grams:
mass = n X atomic mass
= 0.52 x 162.2 (atomic mass of FeCl3 is 162.2grams/mole)
<h3> = 84.34 grams </h3>